Invitrogen™ BRP44L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116938

Catalog No. PIPA5116938

Description

Positive Samples: HepG2, K-562, Mouse liver, Rat heart Immunogen sequence: IISGRMTFAL CCYSLTFMRF AYKVQPRNWL LFACHATNEV AQLIQGGRLI KHEMTKTASA.

BRP44L (brain protein 44-like protein), also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family. The gene that encodes BRP44L maps to human chromosome 6. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Specifications

• Antigen: BRP44L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPC1
• Gene Alias: 0610006G08Rik; 3830411I18Rik; apoptosis-regulating basic protein; Arbp; Brain protein 44-like protein; Brp44l; CGI-129; dJ68L15.3; HSPC040; HSPC040 protein; mitochondrial pyruvate carrier 1; Mpc1; MPYCD; PNAS-115
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171087, 51660, 55951
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 0.57 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P63030, P63031, Q9Y5U8
• Gene Symbols: MPC1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_0571821).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG