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Invitrogen™ BRP44L Polyclonal Antibody
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Catalog No. PIPA5101468
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PIPA5101468 100 μL
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Catalog No. PIPA5101468 Supplier Invitrogen™ Supplier No. PA5101468
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BRP44L.

BRP44L (brain protein 44-like protein), also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family. The gene that encodes BRP44L maps to human chromosome 6. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRP44L
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MPC1
Gene Accession No. P63030, P63031, Q9Y5U8
Gene Alias 0610006G08Rik; 3830411I18Rik; apoptosis-regulating basic protein; Arbp; Brain protein 44-like protein; Brp44l; CGI-129; dJ68L15.3; HSPC040; HSPC040 protein; mitochondrial pyruvate carrier 1; Mpc1; MPYCD; PNAS-115
Gene Symbols MPC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human MPC1(Accession Q9Y5U8), corresponding to amino acid residues R19-F69.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171087, 51660, 55951
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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