Invitrogen™ BRWD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558620

Catalog No. PIPA558620

Description

Immunogen sequence: ILILDLEVNQ TVGVIAIERT GVPFLQVIPC FQRDGLFCLH ENGCITLRVR RSYNNIFTTS NEEPDPDPVQ ELTYDLRSQC D Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.

WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

Specifications

• Antigen: BRWD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR11
• Gene Alias: 2900055P10Rik; AW489876; bromodomain and WD repeat domain containing 2; bromodomain and WD repeat-containing protein 2; BRWD2; DR11; HH14; Kiaa1351; mKIAA1351; sensitization to ricin complex subunit 1; SRI1; WD repeat domain 11; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR11; WDR15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55717
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BZH6
• Gene Symbols: WDR11
• Immunogen: Recombinant protein corresponding to Human BRWD2. Recombinant protein control fragment (Product #RP-97074).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG