Invitrogen™ BRWD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588006

Catalog No. PIPA588006

Description

Immunogen sequence: YFQKFQLERV NLQEVKRSTY DHTRKCTDQL LLLGQTDRAV QLLLETSADN QHYYCDSLKA CLVTTVTSSG PSQSTIKLVA TNMIANGKLA EGVQLLCLID KAADACRYLQ TYGEWNRAAW LAKVRLNPEE CADVLRRWVD HLCSPQVNQK SKALLVLLSL GCFFSVAETL HSMRYFDRAA LFVEACLKYG AFEVTEDTEK LITAIYADYA RSLKNLGFKQ GAVLFASKAG AAGKDLLNEL ESPKEEPIEE; Positive Samples: DU145, HL-60, HepG2; Cellular Location: Cytoplasm, Membrane, Nucleus, Single-pass membrane protein.

WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

Specifications

• Antigen: BRWD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR11
• Gene Alias: 2900055P10Rik; AW489876; bromodomain and WD repeat domain containing 2; bromodomain and WD repeat-containing protein 2; BRWD2; DR11; HH14; Kiaa1351; mKIAA1351; sensitization to ricin complex subunit 1; SRI1; WD repeat domain 11; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR11; WDR15
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55717
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BZH6
• Gene Symbols: WDR11
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 975-1224 of human WDR11 (NP_0605878).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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