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Invitrogen™ BRWD2 Polyclonal Antibody
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Catalog No. PIPA588006
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100 μL
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PIPA588006 100 μL
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Catalog No. PIPA588006 Supplier Invitrogen™ Supplier No. PA588006
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YFQKFQLERV NLQEVKRSTY DHTRKCTDQL LLLGQTDRAV QLLLETSADN QHYYCDSLKA CLVTTVTSSG PSQSTIKLVA TNMIANGKLA EGVQLLCLID KAADACRYLQ TYGEWNRAAW LAKVRLNPEE CADVLRRWVD HLCSPQVNQK SKALLVLLSL GCFFSVAETL HSMRYFDRAA LFVEACLKYG AFEVTEDTEK LITAIYADYA RSLKNLGFKQ GAVLFASKAG AAGKDLLNEL ESPKEEPIEE; Positive Samples: DU145, HL-60, HepG2; Cellular Location: Cytoplasm, Membrane, Nucleus, Single-pass membrane protein.

WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRWD2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene WDR11
Gene Accession No. Q9BZH6
Gene Alias 2900055P10Rik; AW489876; bromodomain and WD repeat domain containing 2; bromodomain and WD repeat-containing protein 2; BRWD2; DR11; HH14; Kiaa1351; mKIAA1351; sensitization to ricin complex subunit 1; SRI1; WD repeat domain 11; WD repeat domain 15; WD repeat-containing protein 11; WD repeat-containing protein 15; WDR11; WDR15
Gene Symbols WDR11
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 975-1224 of human WDR11 (NP_0605878).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55717
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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