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  5. Tocris Bioscience™ BS 181 dihydrochloride

Tocris Bioscience™ BS 181 dihydrochloride
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Catalog No. 560850
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective cdk7 inhibitor

BS 181 dihydrochloride is a selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over other cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.

Specifications

Chemical Name or Material N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
CAS 1883548-83-1
Quantity 50 mg
Target Cyclin-dependent Kinase Inhibitors
Molecular Formula C22H32N6.2HCl
Formula Weight 453.45
Purity >99%
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