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Tocris Bioscience™ BSJ-03-204
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Catalog No. 69385
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69-385 5 mg
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Catalog No. 69-385 Supplier Tocris Bioscience™ Supplier No. 6938/5
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Description

Selective Cdk4/6 degrader

BSJ-03-204 is a selective Cdk4/6 Degrader (PROTAC™). Displays cereblon-dependent degradation with no effect on IKZF1/3 in Molt4 cells. Induces degradation of Cdk4/6 and G1 cell cycle arrest, and inhibits cell proliferation in a mantle cell lymphoma (MCL) cell line.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material N-[4-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
CAS 2349356-09-6
Quantity 5 mg
Molecular Formula C43H48N10O8
Purity 98%
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