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Invitrogen™ BTBD12 Polyclonal Antibody
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Catalog No. PIPA564270
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100 μL
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PIPA564270 100 μL
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Catalog No. PIPA564270 Supplier Invitrogen™ Supplier No. PA564270
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LIQYVNNEGF SAVEDGVLTQ RVLLGDVSTE AARTFLHYLY TADTGLPPGL SSELSSLAHR FGVSELVHLC EQVPIATDSE GKPWEEKEAE NCESRA Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 69%.

This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BTBD12
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLX4
Gene Accession No. Q8IY92
Gene Alias BTB (POZ) domain containing 12; BTB/POZ domain-containing protein 12; BTBD12; FANCP; KIAA1784; KIAA1987; MUS312; SLX4; SLX4 structure-specific endonuclease subunit; SLX4 structure-specific endonuclease subunit homolog; structure-specific endonuclease subunit SLX4
Gene Symbols SLX4
Host Species Rabbit
Immunogen Recombinant protein fragment of Human SLX4 (Product #RP-103627)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84464
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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