Invitrogen™ BTBD7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA545934

Catalog No. PIPA545934

Description

Peptide sequence: SPRVGGNSQA QQTFIGTSSY SQQGYGCESK LYSLDHGHEK PQDKKKRTSG Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 79%.

Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt].

Specifications

• Antigen: BTBD7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BTBD7
• Gene Alias: 5730507E09Rik; 8030448M07; BTB (POZ) domain containing 7; BTB domain containing 7; BTB/POZ domain-containing protein 7; Btbd7; E130118E17Rik; function-unkown protein 1; Fup1; Kiaa1525; mKIAA1525; si:dkeyp-55f12.1; wu:fd08g07
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55727
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9P203
• Gene Symbols: BTBD7
• Immunogen: Synthetic peptide directed towards the N-terminal of human BTBD7 (aa 13-62).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov