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Invitrogen™ BTBD7 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA5142661
This item is not returnable.
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Description
Additional Information: This antibody is expected to recognize both reported isoforms (NP_001002860.2; NP_060637.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt].
Specifications
BTBD7 | |
Polyclonal | |
Unconjugated | |
BTBD7 | |
5730507E09Rik; 8030448M07; BTB (POZ) domain containing 7; BTB domain containing 7; BTB/POZ domain-containing protein 7; Btbd7; E130118E17Rik; function-unkown protein 1; Fup1; Kiaa1525; mKIAA1525; si:dkeyp-55f12.1; wu:fd08g07 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
238386 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q8CFE5 | |
BTBD7 | |
Peptide with sequence ESKLYSLDHGHEKPQ-C (aa 40-54). | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
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