Btk Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA527392

Catalog No. PIPA527392

Description

PA5-27392 targets BTK in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27392 immunogen is recombit fragment corresponding to a region within amino acids 429 and 659 of Human BTK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Specifications

• Antigen: BTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q06187
• Gene Symbols: BTK
• Immunogen: Recombit fragment corresponding to a region within amino acids 429 and 659 of Human BTK
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.62 mg/mL
• Gene: BTK
• Gene Alias: AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA, B-cell progenitor kinase, agammaglobulinaemia tyrosine kinase, domit-negative kinase-deficient Brutons tyrosine kinase, tyrosine-protein kinase BTK, tyrosine-protein kinase BTK isoform (lacking exon 14)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 695
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid