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BTLA Monoclonal Antibody (OTI4C2), TrueMAB™, OriGene
SDP

Catalog No. 501676006
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50-167-6006 100 μL
50-253-9629 30 μL
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Catalog No. 50-167-6006 Supplier OriGene Supplier No. TA505547
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Description

Mouse Monoclonal Antibody

BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily. BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM). This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

Specifications

Antigen BTLA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene BTLA
Gene Accession No. Q7Z6A9
Gene Alias BTLA1, CD272
Gene Symbols BTLA
Host Species Mouse
Immunogen Full length human recombit protein of human BTLA produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151888
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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