BTLA Mouse anti-Human, Clone: OTI4C2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505547

Catalog No. 50-166-3725

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily. BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM). This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.

Specifications

• Antigen: BTLA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: BTLA
• Gene Alias: BTLA1, CD272
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 151888
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4C2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q7Z6A9
• Gene Symbols: BTLA
• Immunogen: Full length human recombit protein of human BTLA produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b