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Invitrogen™ BTLA Polyclonal Antibody
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Catalog No. PIPA597029
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100 μL
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PIPA597029 100 μL
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Catalog No. PIPA597029 Supplier Invitrogen™ Supplier No. PA597029
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KESCDVQLYI KRQSEHSILA GDPFELECPV KYCANRPHVT WCKLNGTTCV KLEDRQTSWK EEKNISFFIL HFEPVLPNDN GSYRCSANFQ SNLIESHSTT LYVTGKQNEL SDTAGREINL VDAHLKSEQT EASTRQNSQV LLSETGIYDN DPDLCFRMQE GSEVYSNPCL EENKPGIVYA SLNHSVIGPN SRLARNVKEA PTEYASICVR S; Positive Samples: Mouse spleen, Mouse thymus, Rat lung; Cellular Location: Membrane, Single-pass type I membrane protein.

BTLA or B and T-lymphocyte attenuator is a member of the co-inhibitory receptors of the CD28 superfamily. BTLA is a lymphocyte inhibitory receptor which inhibits lymphocytes during immunes responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells and its expression progressively decreases upon T cell activation. It remains expressed on Th1 cells, but not Th2 cells. BTLA is a unique co-receptor that interacts with the tumor necrosis factor receptor superfamily member herpesvirus entry mediator (HVEM). This interation is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BTLA
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene BTLA
Gene Accession No. Q6PNM1, Q7TSA3
Gene Alias A630002H24; B and T lymphocyte associated; B and T lymphocyte associated protein; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA_HUMAN; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743
Gene Symbols BTLA
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 31-241 of human BTLA (NP_0010788261).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 208154, 407756
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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