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Invitrogen™ BTNL2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA577142
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
Specifications
BTNL2 | |
Polyclonal | |
Unconjugated | |
BTNL2 | |
Btl2; BTL-II; BTLN2; BTN7; BTNL2; butyrophilin like 2; butyrophilin-like 2; butyrophilin-like 2 (MHC class II associated); butyrophilin-like protein 2; butyrophylin-like MHC class II associated; Gm315; HSBLMHC1; NG9; SS2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
547431, 56244 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide | |
O70355, Q9UIR0 | |
BTNL2 | |
Recombinant full length Human BTNL2. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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