Invitrogen™ BTNL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577142

Catalog No. PIPA577142

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.

Specifications

• Antigen: BTNL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BTNL2
• Gene Alias: Btl2; BTL-II; BTLN2; BTN7; BTNL2; butyrophilin like 2; butyrophilin-like 2; butyrophilin-like 2 (MHC class II associated); butyrophilin-like protein 2; butyrophylin-like MHC class II associated; Gm315; HSBLMHC1; NG9; SS2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 547431, 56244
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O70355, Q9UIR0
• Gene Symbols: BTNL2
• Immunogen: Recombinant full length Human BTNL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG