Invitrogen™ BTNL2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5109458	100 μL

Catalog No. PIPA5109458 Supplier Invitrogen™ Supplier No. PA5109458

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKVNGPSQPI LVRVGEDIQL TCYLSPKANA QSMEVRWDRS HRYPAVHVYM DGDHVAGEQM AEYRGRTVLV SDAIDEGRLT LQILSARPSD DGQYRCLFEK DDVYQEASLD LKVVSLGSSP LITVEGQEDG EMQPMCSSDG WFPQPHVPWR DMEGKTIPSS SQALTQGSHG LFHVQTLLRV TNISAVDVTC SISIPFLGEE KIATFSLSGW.

BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.

Specifications

• Antigen: BTNL2
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 2.61 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: BTNL2
• Gene Accession No.: O70355, Q6MG97, Q9UIR0
• Gene Alias: Btl2; BTL-II; BTLN2; BTN7; BTNL2; butyrophilin like 2; butyrophilin-like 2; butyrophilin-like 2 (MHC class II associated); butyrophilin-like protein 2; butyrophylin-like MHC class II associated; Gm315; HSBLMHC1; NG9; SS2
• Gene Symbols: BTNL2
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 309620, 547431, 56244
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG