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  5. Tocris Bioscience™ BTT 3033

Tocris Bioscience™ BTT 3033
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Catalog No. 472450
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50 mg
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Catalog No. Quantity
47-245-0 50 mg
47-241-0 10 mg
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Catalog No. 47-245-0 Supplier Tocris Bioscience™ Supplier No. 4724/50
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Description

Selective inhibitor of integrin α2β1

BTT 3033 is a selective inhibitor of integrin α2β1 (EC50 = 130 nM for α2β1 binding to collagen I). Binds to the α2I domain. Exhibits selectivity for α2β1 over integrins α3β1, α4β1, α5β1 and αv. BTT 3033 inhibits platelet aggregation to collagen I coated capillaries under flow and inhibits binding of α2-expressing CHO cells to collagen I under shear stress conditions. Neurogenic and thromboxane A2-induced human prostate smooth muscle contraction are also inhibited by BTT 3033.

Specifications

Quantity 50 mg
Product Type BTT 3033
Purity >98%
Molecular Weight (g/mol) 465.5
Inhibitors BTT 3033

For Research Use Only

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