Invitrogen™ Bu-1a Monoclonal Antibody (21-1A4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528755

Catalog No. PIMA528755

Description

Bu-1a Monoclonal Antibody for Flow

Bu-1, a product of the Bu-1a and Bu-1b alleles, is a type I transmembrane glycosylated disulfide-linked homodimer. The monoclonal antibody AV20 recognizes a monomorphic determinant on the Bu-1 B cell-associated alloantigens of both RPL 6(3) (Bu-1a) and 7(2) (Bu-1b) lines of inbred chickens. The antibody also identifies B cells in partially inbred birds. Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. The monoclonal antibody AV20 does not cross react with turkey cells when analyzed by flow cytometry.

Specifications

• Antigen: Bu-1a
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: BBS with Proprietary stabilizer and no preservative; pH 8.2
• Gene Accession No.: 0
• Gene Symbols: LOC396098
• Immunogen: Bursa cells from one-day-old H.B15 (Bu-1a/b) strain chickens.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Chicken
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: 21-1A4
• Conjugate: Unconjugated
• Gene: LOC396098
• Gene Alias: B6.1; B6.2; Bu-1; Bu-1b; ChB6.1; LOC396098
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 396098
• Content And Storage: 4°C
• Form: Liquid