Bumetanide, 98+%, PROMO, Thermo Scientific Chemicals

Description

Inhibitor of the sodium-potassium-chloride cotransporter

Applications

Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Solubility

Soluble in ethanol (10 mg/mL), DMSO (25 mg/mL), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.

Specifications

Chemical Identifiers

• CAS: 28395-03-1
• Molecular Formula: C17H20N2O5S
• Molecular Weight (g/mol): 364.42 g/mol
• MDL Number: MFCD00078949
• InChI Key: MAEIEVLCKWDQJH-UHFFFAOYSA-N
• Synonym: bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
• PubChem CID: 2471
• ChEBI: CHEBI:3213
• IUPAC Name: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
• SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

• Melting Point: 230°C to 231°C
• Color: White
• Quantity: 5 g
• Merck Index: 14,1484
• Solubility Information: Soluble in ethanol, DMSO, acetone, benzene, methanol, propylene glycol, and water.
• Percent Purity: ≥98%
• Physical Form: Solid
• Chemical Name or Material: Bumetanide

Safety and Handling

EINECSNumber	249-004-6
RTECSNumber	DG4910000
TSCA	No

RUO - Research Use Only