Invitrogen™ BVES Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102304

Catalog No. PIPA5102304

Description

Antibody detects endogenous levels of total BVES.

Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.

Specifications

• Antigen: BVES
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BVES
• Gene Alias: blood vessel epicardial substance; bves; hBVES; LGMD2X; mBVES; MGC42413; POP 1; POP1; POPDC 1; Popdc1; popdc1 protein; popeye 1; popeye domain containing 1; popeye domain-containing 1; popeye domain-containing protein 1; Popeye protein 1; zgc:86887
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11149, 23828, 365603
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3BCU4, Q8NE79, Q9ES83
• Gene Symbols: BVES
• Immunogen: A synthesized peptide derived from human BVES(Accession Q8NE79), corresponding to amino acid residues S174-N224.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG