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Tocris Bioscience™ BVT 948

Catalog No. 217650
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50 mg
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Catalog No. Quantity
21-765-0 50 mg
21-761-0 10 mg
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Catalog No. 21-765-0 Supplier Tocris Bioscience™ Supplier No. 2176/50
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Description

Non-competitive protein tyrosine phosphatase inhibitor

BVT 948 is a non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Also inhibits several cytochrome P450 isoforms (IC50 <10 μM).

Specifications

Quantity 50 mg
Product Type BVT 948
Purity >98%
Molecular Weight (g/mol) 241.25
Inhibitors BVT 948

For Research Use Only

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