Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEPA5144528

Invitrogen™ BZLF1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. FEPA5144528
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEPA5144528 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEPA5144528 Supplier Invitrogen™ Supplier No. PA5144528
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

BZLF1 Polyclonal Antibody for Western Blot, ELISA

Transcription factor that acts as a molecular switch to induce the transition from the latent to the lytic or productive phase of the virus cycle (PubMed:8404860) (Probable). Mediates the switch from the latent to the lytic cycle of infection in cells containing a highly methylated viral genome (PubMed:34893887, PubMed:15361873). Probably binds to silenced chromatin and recruits host chromatin-remodeling enzymes (PubMed:30926617). Regulates this switch by binding to 2 types of ZEBRA response elements (ZREs): the CpG-free AP-1 like elements (latency) and the methylated CpG-containing elements (lytic replication) (PubMed:34893887, PubMed:22022468) (Probable). Activates preferentially the methylated forms of the viral lytic R (BRLF1) and Na (BRRF1) gene promoters, the latters being the first genes activated during Z-mediated reactivation in latently infected cells (PubMed:19325883, PubMed:15361873). BZLF1 and BRLF1 act together to trigger lytic replication (PubMed:10856251, PubMed:15361873). Also binds the lytic origin of replication, oriLyt (PubMed:20808903). Induces G1 cell cycle arrest by stabilizing the host CCAAT/enhancer binding protein CEBPA (PubMed:15078966). This function is important because the lytic cycle preferentially takes place in host cells arrested in G1 (PubMed:15078966).
TRUSTED_SUSTAINABILITY

Specifications

Antigen BZLF1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene BZLF1
Gene Accession No. P03206
Gene Alias Trans-activator protein BZLF1
Gene Symbols BZLF1
Host Species Rabbit
Immunogen Recombinant Epstein-Barr virus BZLF1 protein.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3783744
Target Species Virus
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.