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Tocris Bioscience™ c-Di-GMP sodium salt
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Catalog No. 5900730U
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730 μg
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Catalog No. Quantity
5900730U 730 μg
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Catalog No. 5900730U Supplier Tocris Bioscience™ Supplier No. 5900/730U
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Description

Endogenous STING and DDX41 agonist; activates STING-dependent signaling

c-Di-GMP sodium salt is an endogenous STING and DDX41 agonist; mediates DDX41-STING interaction. Activates STING-dependent IFN-β production in mouse and human cells. Also induces an antitumor response in a lung B16-10 melanoma mouse model, when administered intravenously within YSKO5-liposomes.

This product is sold in units of 730μg, equivalent to 1μmol.

Specifications

Chemical Name or Material 3′,5′-Cyclic diguanylic acid sodium salt
Synonym endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membr
Quantity 730 μg
Target STING/TMEM173
Molecular Formula C20H22N10Na2O14P2
Formula Weight 734.37
Purity >98%
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