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Tocris Bioscience™ C-DIM 12
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Catalog No. 582150
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Catalog No. Quantity
58-215-0 50 mg
58-211-0 10 mg
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Catalog No. 58-215-0 Supplier Tocris Bioscience™ Supplier No. 5821/50
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Description

Nurr1 activator; inhibits NF-κB-dependent gene expression

Nurr1 activator. Inhibits NF-κB and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters. Neuroprotective in a mouse Parkinson's disease model. Orally bioavailable.

Chemical Identifiers

CAS 178946-89-9
Molecular Formula C23H17ClN2

Specifications

Quantity 50 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 356.85
Physical Form Solid
Purity >98%
Molecular Weight (g/mol) 356.85
Chemical Name or Material 3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole]

Safety and Handling

Recommended Storage Store at -20°C
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