Invitrogen™ C/EBP epsilon Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536202

Catalog No. PIPA536202

Description

This antibody detects endogenous protein at a molecular weight of 30 and 45 kDa. Purity is >95% by SDS-PAGE.

C/EBP alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP alpha appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP alpha.

Specifications

• Antigen: C/EBP epsilon
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CEBPE
• Gene Alias: C EBP; c/EBP epsilon; C/EBPe; C/EBPepsilon; C/EBP-epsilon; C/EBP-related protein 1; C/EPBe; CCAAT/enhancer binding protein (C/EBP), epsilon; CCAAT/enhancer binding protein , epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; Crp1; Gm294
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1053, 110794, 25410
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P56261, Q15744, Q6PZD9
• Gene Symbols: CEBPE
• Immunogen: Synthetic peptide corresponding to amino acids 188-245 of human C/EBP- epsilon.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG