Invitrogen™ c-Jun Monoclonal Antibody (5B1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515881

Catalog No. PIMA515881

Description

MA5-15881 targets c-Jun in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples. The MA5-15881 immunogen is purified recombinant fragment of human c-Jun expressed in E. Coli. . MA5-15881 detects c-Jun which has a predicted molecular weight of approximately 43kDa.

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.

Specifications

• Antigen: c-Jun
• Classification: Monoclonal
• Concentration: Conc. not determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P05412, P05627
• Gene Symbols: JUN
• Immunogen: Purified recombinant fragment of human c-Jun expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 16476, 3725
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5B1
• Conjugate: Unconjugated
• Gene: JUN
• Gene Alias: Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG1

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov