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c-Jun Polyclonal Antibody, Invitrogen™

Catalog No. PA1833
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200 μg
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PA1833 200 μg
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Catalog No. PA1833 Supplier Thermo Scientific Supplier No. PA1833

Description

Rabbit Polyclonal Antibody

PA1-833 detects cJun from mouse cells. PA1-833 has been successfully used in Western blot and ChIP procedures. By Western blot, this antibody detects an ∽40 kDa protein representing cJun in NIH 3T3 serum stimulated cells. A smaller band is also detected at ∽26 kDa possibly representing a proteolytic fragment of cJun. The PA1-833 immunogen is a synthetic peptide corresponding to residues T(91) P T P T Q F L C P K N V T D(105) of mouse cJun. Reconstitute in 200 μL PBS to create a stock of 1 mg/mL.

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen c-Jun
Applications ChIP Assay, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation antibody with 0.05% sodium azide
Gene JUN
Gene Accession No. P05627
Gene Alias Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Gene Symbols JUN
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues T(91) P T P T Q F L C P K N V T D(105) of mouse cJun.
Purification Method IgG fraction
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16476
Target Species Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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