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c-Myc Mouse, Clone: CT14.G4, Novus Biologicals™
SDP

Catalog No. p-7105462 Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP232960B 0.2 mg
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Catalog No. NBP232960B Supplier Novus Biologicals Supplier No. NBP2329600.2MG

Description

Mouse Monoclonal Antibody

c-Myc Monoclonal antibody specifically detects Antigen in Human, Mouse (Negative), Primate samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen c-Myc
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone CT14.G4
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01106
Gene Alias avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
Gene Symbols MYC
Host Species Mouse
Immunogen A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQL-RNSCA) from C-terminus of human c-myc, coupled to KLH
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Autophagy, Cancer, Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, Epitope Tags, Myc Epitope Tags, Phospho Specific, Stem Cell Markers, Transcription Factors and Regulators, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 4609
Test Specificity The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Target Species Human, Primate, Mouse (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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