Invitrogen™ C-Peptide Monoclonal Antibody (C-PEP-01), Biotin

Catalog No.	Quantity
PIMA110317	100 μg

Catalog No. PIMA110317 Supplier Invitrogen™ Supplier No. MA110317

Description

Mouse Monoclonal Antibody

This antibody reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.

Specifications

• Antigen: C-Peptide
• Applications: ELISA, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Immunocytochemistry
• Classification: Monoclonal
• Clone: C-PEP-01
• Concentration: 1 mg/mL
• Conjugate: Biotin
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene: INS
• Gene Accession No.: P01308
• Gene Alias: Cpeptide; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin
• Gene Symbols: INS
• Host Species: Mouse
• Immunogen: Human C-peptide conjugated to bovine serum albumin.
• Purification Method: Size-exclusion chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3630
• Target Species: Human
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1