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Invitrogen™ C. rhodostoma Snaclec rhodocytin subunit alpha Polyclonal Antibody
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Catalog No. PIPA5117723
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100 μg
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PIPA5117723 100 μg
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Catalog No. PIPA5117723 Supplier Invitrogen™ Supplier No. PA5117723
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C. rhodostoma Snaclec rhodocytin subunit alpha
Applications Western Blot
Classification Polyclonal
Concentration 3.609 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Alias Rhodoaggretin subunit alpha
Host Species Rabbit
Immunogen Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136aa).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Reptile
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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