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Invitrogen™ C11orf85 Polyclonal Antibody
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Catalog No. PIPA534721
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100 μL
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PIPA534721 100 μL
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Catalog No. PIPA534721 Supplier Invitrogen™ Supplier No. PA534721
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

C11orf85, also known as PCIF1 (phosphorylated CTD-interacting factor 1), is located on chromosome 11. This gene encodes a protein that plays a critical role in post-transcriptional modification and regulation processes. PCIF1 is involved in the methylation of mRNA, specifically adding a methyl group to the 2'-O position of the first nucleotide adjacent to the cap structure of mRNA. This cap-specific mRNA (nucleoside-2'-O-)-methyltransferase activity is crucial for mRNA stability, translation, and the regulation of gene expression. The PCIF1 protein also has interactions with RNA polymerase II and is involved in the maturation and processing of nascent mRNA transcripts. Studies have shown that the disruption of PCIF1 function can lead to altered RNA metabolism and has potential implications in a variety of cellular processes, including immune responses and ferroptosis resistance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C11orf85
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene MAJIN
Gene Accession No. Q3KP22
Gene Alias C11orf85; CK085; LOC283129; MAJIN; membrane anchored junction protein; membrane-anchored junction protein; uncharacterized protein C11orf85
Gene Symbols MAJIN
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human LOC283129. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283129
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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