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C12ORF61 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989482
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50-198-9482 100 μL
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Catalog No. 50-198-9482 Supplier Bioss Supplier No. BS9953R
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Rabbit Polyclonal Antibody

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf61 gene product has been provisionally designated C12orf61 pending further characterization.

Specifications

Antigen C12ORF61
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LINC01465
Gene Accession No. Q8N7H1
Gene Symbols LINC01465
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human C12ORF61.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283416
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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