C17orf37 Mouse anti-Human, Clone: OTI1D4, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA504626S

Catalog No. 50-167-5275

Description

During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3 ft. end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.

Specifications

• Antigen: C17orf37
• Classification: Monoclonal
• Concentration: 0.98 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9BRT3
• Gene Alias: C17orf37, C35, ORB3, RDX12, XTP4
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 30 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 84299

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D4
• Conjugate: Unconjugated
• Gene: MIEN1
• Format: Liquid
• Gene Symbols: MIEN1
• Immunogen: Full length human recombit protein of human C17orf37 produced in E.coli.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human