C17orf37 Mouse anti-Human, Clone: OTI1D4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504626

Catalog No. 50-166-3030

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3′ end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.

Specifications

• Antigen: C17orf37
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MIEN1
• Gene Alias: C17orf37, C35, ORB3, RDX12, XTP4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84299
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9BRT3
• Gene Symbols: MIEN1
• Immunogen: Full length human recombit protein of human C17orf37 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1