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Invitrogen™ C17orf85 Polyclonal Antibody
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Catalog No. PIPA552633
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100 μL
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PIPA552633 100 μL
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Catalog No. PIPA552633 Supplier Invitrogen™ Supplier No. PA552633
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRVSVKAEAP AGPALGLPSP EAESGVDRGE PEPMEVEEGE LEIVPVRRSL KELIPDTSRR YENKAGSFIT GIDVTSKEAI EKKEQRAKRF HFRSEVNLAQ RNVALDRDMM KKAIPKVRLE TIYICGVD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C17orf85
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NCBP3
Gene Accession No. Q53F19
Gene Alias 1200014J11Rik; C11H17orf85; C130061O14Rik; C17orf85; C19H17orf85; C78393; C9H17orf85; CTD-3195I5.1; CTD-3195I5.5; ELG; ELG protein; HSA277841; Ncbp3; nuclear cap binding subunit 3; nuclear cap-binding protein subunit 3; Protein ELG; RGD1308139; RIKEN cDNA 1200014J11 gene; similar to RIKEN cDNA 1200014J11; uncharacterized protein C17orf85 homolog
Gene Symbols NCBP3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C17orf85. Recombinant protein control fragment (Product #RP-89979).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55421
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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