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C17orf85 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734329 Shop All Proteintech Group Inc Products
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50-173-4329 150 μL
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Catalog No. 50-173-4329 Supplier Proteintech Group Inc Supplier No. 243841AP150UL
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Description

Rabbit Polyclonal Antibody

Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.

Specifications

Antigen C17orf85
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NCBP3
Gene Accession No. Q53F19
Gene Alias C17orf85, ELG, HSA277841, Protein ELG
Gene Symbols NCBP3
Host Species Rabbit
Immunogen C17orf85 Fusion Protein Ag20021
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55421
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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