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Invitrogen™ C17orf96 Polyclonal Antibody
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Catalog No. PIPA565930
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100 μL
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PIPA565930 100 μL
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Catalog No. PIPA565930 Supplier Invitrogen™ Supplier No. PA565930
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETLCPAPRLAV PASPRGSPCS PTPRKPCRGT QEFSPL Highest antigen sequence identity to the following orthologs - mouse 89%, rat 92%.

Elongin BC and Polycomb repressive complex 2-associated protein (EPOP) also know as C17ORF96 is a scaffold protein that serves as a bridging partner between the PRC2/EED-EZH2 complex and the elongin BC complex. It is required to fine tune the transcriptional status of polycomb group (PcG) target genes in embryonic stem cells (ESCs). C17ORF96 also plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression of PcG target genes. It acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EED-EZH2 complex. C17ORF96 also has interacts with USP7 and promotes deubiquitination of H2B at promoter sites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C17orf96
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene EPOP
Gene Accession No. A6NHQ4
Gene Alias AA409164; AI413509; AW539173; C17orf96; C9H17orf96; chromosome 17 open reading frame 96; CUNH17orf96; E13; E130012A19Rik; elongin BC and polycomb repressive complex 2 associated protein; elongin BC and Polycomb repressive complex 2-associated protein; Embryonic stem cell-specific PRC2 subunit p48; EPOP; ES cell-specific PRC2 subunit p48; esPRC2p48; hypothetical protein LOC691153; LOC691153; proline rich 28; Proline-rich protein 28; PRR28; RIKEN cDNA E130012A19 gene; uncharacterized protein C17orf96; uncharacterized protein C17orf96 homolog; Uncharacterized protein ENSP00000317905
Gene Symbols EPOP
Host Species Rabbit
Immunogen Recombinant Human C17orf96. Recombinant protein control fragment (Product #RP-106610).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100170841
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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