Invitrogen™ C17orf96 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565930

Catalog No. PIPA565930

Description

Immunogen sequence: ETLCPAPRLAV PASPRGSPCS PTPRKPCRGT QEFSPL Highest antigen sequence identity to the following orthologs - mouse 89%, rat 92%.

Elongin BC and Polycomb repressive complex 2-associated protein (EPOP) also know as C17ORF96 is a scaffold protein that serves as a bridging partner between the PRC2/EED-EZH2 complex and the elongin BC complex. It is required to fine tune the transcriptional status of polycomb group (PcG) target genes in embryonic stem cells (ESCs). C17ORF96 also plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression of PcG target genes. It acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EED-EZH2 complex. C17ORF96 also has interacts with USP7 and promotes deubiquitination of H2B at promoter sites.

Specifications

• Antigen: C17orf96
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPOP
• Gene Alias: AA409164; AI413509; AW539173; C17orf96; C9H17orf96; chromosome 17 open reading frame 96; CUNH17orf96; E13; E130012A19Rik; elongin BC and polycomb repressive complex 2 associated protein; elongin BC and Polycomb repressive complex 2-associated protein; Embryonic stem cell-specific PRC2 subunit p48; EPOP; ES cell-specific PRC2 subunit p48; esPRC2p48; hypothetical protein LOC691153; LOC691153; proline rich 28; Proline-rich protein 28; PRR28; RIKEN cDNA E130012A19 gene; uncharacterized protein C17orf96; uncharacterized protein C17orf96 homolog; Uncharacterized protein ENSP00000317905
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100170841
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A6NHQ4
• Gene Symbols: EPOP
• Immunogen: Recombinant Human C17orf96. Recombinant protein control fragment (Product #RP-106610).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov