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C19orf29 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989487
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50-198-9487 100 μL
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Catalog No. 50-198-9487 Supplier Bioss Supplier No. BS9960R
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Description

Rabbit Polyclonal Antibody

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.

Specifications

Antigen C19orf29
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CACTIN
Gene Accession No. Q8WUQ7
Gene Alias C19orf29; C20H19orf29; CACTIN; cactin, spliceosome C complex subunit; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24; NY-REN-24 antigen; Renal carcinoma antigen NY-REN-24
Gene Symbols CACTIN
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Cactin/C19orf29.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58509
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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