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Invitrogen™ C19orf48 Polyclonal Antibody
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Catalog No. PIPA559814
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100 μL
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PIPA559814 100 μL
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Catalog No. PIPA559814 Supplier Invitrogen™ Supplier No. PA559814
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MTVLEAVLEI QAITGSRLLS MVPGPARPPG SCWDPTQCTR TWLLSHTPRR RWISGLPR Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 40%.

The C19orf48 gene, located on chromosome 19q13, encodes a protein involved in various biological processes, including its role as a minor histocompatibility antigen recognized by CD8+ T cells. This gene has been implicated in oncogenesis due to its elevated expression in certain cancer types, such as breast cancer, where it has been associated with poor prognosis. The non-synonymous single-nucleotide polymorphisms within C19orf48 contribute to differential T-cell recognition in donor and recipient cells, highlighting its significance in immune responses. Additionally, C19orf48 has been linked with SNORD88C, a small nucleolar RNA (snoRNA) that guides methylation of rRNA, further illustrating its involvement in cellular proliferation and metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C19orf48
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene C19orf48
Gene Accession No. Q6RUI8
Gene Alias C19orf48; chromosome 19 open reading frame 48; multidrug resistance-related protein; Uncharacterized protein C19orf48
Gene Symbols C19orf48
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C19orf48. Recombinant protein control fragment (Product #RP-99147).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84798
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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