Invitrogen™ C19orf52 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559759

Catalog No. PIPA559759

Description

Immunogen sequence: LDVGFVGRWW VLGAWMRDCD INDDEFLHLP AHLRVVGPQQ LHSETNERLF DEKYKPVVLT DDQVDQALWE EQVLQKEKKD Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

TIMM29, also known as C19orf52, is identified as a novel subunit of the human TIM22 complex, which plays a critical role in the mitochondrial inner membrane. This protein is crucial for the stability of the TIM22 complex, which is responsible for the translocation of hydrophobic inner mitochondrial membrane proteins carrying internal targeting signals. TIMM29/C19orf52 is integrated into the mitochondrial inner membrane, exposing its C-terminus to the intermembrane space, and is vital for mitochondrial function and protein import pathways. This gene's importance is underscored by its involvement in processes related to mitochondrial integrity and its potential role in neurodegenerative disorders and viral interactions, such as those with the hepatitis B virus (HBV).

Specifications

• Antigen: C19orf52
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TIMM29
• Gene Alias: 1810026J23Rik; C19orf52; chromosome 19 open reading frame 52; Mitochondrial import inner membrane translocase subunit Tim29; RGD1309188; RIKEN cDNA 1810026J23 gene; similar to hypothetical protein BC011833; TIM29; TIMM29; uncharacterized protein C19orf52; uncharacterized protein C19orf52 homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 315463, 69773, 90580
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8BGX2, Q9BSF4
• Gene Symbols: TIMM29
• Immunogen: Recombinant protein corresponding to Human C19orf52. Recombinant protein control fragment (Product #RP-99123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov