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Invitrogen™ C1orf21 Polyclonal Antibody
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Catalog No. PIPA555432
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PIPA555432 100 μL
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Catalog No. PIPA555432 Supplier Invitrogen™ Supplier No. PA555432
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AKHVATVQNE EEAQKGKNYQ NGDVFGDEYR IKPVEEVKYM KNGAEEEQKI AARNQENLEK SASSNVRLKT NKEVPGLVHQ PRANMHISES QQEFFRMLDE KIEKGRDYCS EE Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C1orf21
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene C1orf21
Gene Accession No. Q9H246
Gene Alias C1orf21; Cell proliferation-inducing gene 13 protein; chromosome 1 open reading frame 21; PIG13; proliferation-inducing protein 13; uncharacterized protein C1orf21
Gene Symbols C1orf21
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C1orf21. Recombinant protein control fragment (Product #RP-89715).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81563
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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