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Invitrogen™ C1orf57 Polyclonal Antibody
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Catalog No. PIPA583002
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100 μL
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PIPA583002 100 μL
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Catalog No. PIPA583002 Supplier Invitrogen™ Supplier No. PA583002
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRNADCSSGP GQRVCVIDEI GKMELFSQLF IQAVRQTLST PGTIILGTIP VPKGKPLALV EEIRN Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 78%.

Belonging to the THEP1 NTPase family, C1orf57 (also known as nucleoside triphosphate phosphohydrolase), and its mouse homolog, 2310079N02Rik, are 190 amino acid proteins that has nucleotide phosphatase activity towards ATP, GTP, TTP, CTP and UTP. Acting as a monomer, it also hydrolyzes nucleoside diphosphates with lower efficiency. The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C1orf57
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ntpcr
Gene Accession No. Q9BSD7
Gene Alias 2310079N02Rik; AI449709; C1orf57; cancer-related nucleoside-triphosphatase; Cancer-related nucleoside-triphosphatase homolog; CH1073-266P11.1; HCR-NTPase; NTPase; Ntpcr; Nucleoside triphosphate phosphohydrolase; nucleoside-triphosphatase C1orf57 homolog; nucleoside-triphosphatase, cancer-related; RGD1306192; RP4-659I19.2; RP4-678E16.2; zgc:92420
Gene Symbols Ntpcr
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NTPCR. Recombinant protein control fragment (Product #RP-94223).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84284
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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