C1orf64 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-3426	100 μL

Catalog No. 50-198-3426 Supplier Bioss Supplier No. BS15073R

Description

Rabbit Polyclonal Antibody

The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Specifications

• Antigen: C1orf64
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: SRARP
• Gene Accession No.: Q8NEQ6
• Gene Alias: C1orf64; chromosome 1 open reading frame 64; ER-related factor; ERRF; Gm694; predicted gene 694; RP11-5P18.4; Srarp; SSPR; Steroid receptor-associated and regulated protein; Steroid receptor-regulated protein; uncharacterized protein C1orf64; uncharacterized protein C1orf64 homolog
• Gene Symbols: SRARP
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human C1orf64.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 149563
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG