Invitrogen™ C1orf96 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560366

Catalog No. PIPA560366

Description

Immunogen sequence: EEQDAEAGDA EAEDAEDAAL PALPVKDVED KPEQQTRTRE TDKSPTSTEP RQQPSALFAR GNRKAVKSPQ RSSSKIKENK HPFALYGW Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.

Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt].

Specifications

• Antigen: C1orf96
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCSAP
• Gene Alias: 1700054N08Rik; AI853424; C1orf96; C4H1orf96; Ccsap; centriole and spindle-associated protein; centriole, cilia and spindle associated protein; centriole, cilia and spindle-associated protein; CSAP; RGD1563235
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126731
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6IQ19
• Gene Symbols: CCSAP
• Immunogen: Recombinant protein corresponding to Human C1orf96. Recombinant protein control fragment (Product #RP-94329).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov