Invitrogen™ C1QBP Monoclonal Antibody (60.11), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548988

Catalog No. FERMA548988

Description

The monoclonal antibody 60.11 is directed against epitopes situated within the NH2-terminal stretch of gC1q-R corresponding to residues 76-93. Clone 60.11 recognizes the putative C1q binding site and reacts with the mature form, but has poor or no reactivity with the truncated form, lacking residues 74-95.

Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.

Specifications

• Antigen: C1QBP
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide
• Gene Accession No.: Q07021
• Gene Symbols: C1QBP
• Immunogen: Recombinant GC1q-R corresponding to mature GC1q-R (amino acids 74-282).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Functional Assay, Inhibition Assays, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 60.11
• Conjugate: FITC
• Gene: C1QBP
• Gene Alias: AA407365; AA986492; ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1QBP; complement C1q binding protein; complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; D11Wsu182e; GC1QBP; gC1qR; gC1Q-R; gC1q-R protein; glycoprotein gC1qBP; HABP1; Hyaluronan-binding protein 1; mitochondrial matrix protein p32; p32; p33; RPA; SF2AP32; SF2p32; splicing factor SF2-associated protein
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 708
• Content And Storage: 4°C, store in dark
• Form: Liquid