Invitrogen™ C1QBP Monoclonal Antibody (74.5.2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548989

Catalog No. FERMA548989

Description

The monoclonal antibody 74.5.2 is directed against epitopes in the XC15 peptide that contains a binding site for high-molecular-weight kininogen and Factor XII. Clone 74.5.2 recognizes both the mature (74-282) and truncated form, lacking residues 74-95.

Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.

Specifications

• Antigen: C1QBP
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: Q07021
• Gene Symbols: C1QBP
• Immunogen: Recombinant gC1q-R corresponding to mature GC1q-R (amino acids 74-282).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Functional Assay, Inhibition Assays, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 74.5.2
• Conjugate: Unconjugated
• Gene: C1QBP
• Gene Alias: AA407365; AA986492; ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1QBP; complement C1q binding protein; complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; D11Wsu182e; GC1QBP; gC1qR; gC1Q-R; gC1q-R protein; glycoprotein gC1qBP; HABP1; Hyaluronan-binding protein 1; mitochondrial matrix protein p32; p32; p33; RPA; SF2AP32; SF2p32; splicing factor SF2-associated protein
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 708
• Content And Storage: 4°C
• Form: Liquid