Invitrogen™ C1QC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551583

Catalog No. PIPA551583

Description

Immunogen sequence: GIPGEPGEEG RYKQKFQSVF TVTRQTHQPP APNSLIRFNA VLTNPQGDYD TSTGKFTCKV PGLYYFVYHA SHTANLCVLL YRSGVKVVTF CGHTSKTNQV NSGGVLLRLQ VGEEVWLAVN DYYDMVGIQG SD Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 73%.

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Specifications

• Antigen: C1QC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1QC
• Gene Alias: AI385742; C1qc; C1Q-C; C1qg; Ciqc; complement C1q C chain; complement C1q subcomponent subunit C; complement component 1, q subcomponent, C chain; complement component 1, q subcomponent, c polypeptide; complement component 1, q subcomponent, gamma polypeptide
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 714
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P02747
• Gene Symbols: C1QC
• Immunogen: Recombinant protein corresponding to Human C1QC. Recombinant protein control fragment (Product #RP-95389).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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