Invitrogen™ C1r Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564877

Catalog No. PIPA564877

Description

Immunogen sequence: DLDTSSNAVD LLFFTDESGD SRGWKLRYTT EIIKCPQPKT LDEFTIIQNL QPQYQFRDYF IATCKQGYQL IEGNQVLHSF TAVCQDDGTW HRAMPRCKIK DCGQPRNLPN GDFRYTTTMG VNTYKARIQY YCHEPYYKMQ TRAGSRESEQ GVYTCTAQGI WKNEQKGEKI PRCLPVCGKP VNPVEQRQRI IGGQ Highest antigen sequence identity to the following orthologs - mouse 84%, rat 87%.

C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1r has a molecular weight of 83,000 and is present in plasma in an average concentration of 50 μg/mL, either as a complex with C1q and C1s or in the absence of C1q as a tetramer with C1s. The subcomponents of the C1 complex are responsible for the initiation of the classical pathway of complement activation.

Specifications

• Antigen: C1r
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1R
• Gene Alias: AI132558; C1r; C1ra; complement C1r; complement C1r subcomponent; Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain; Complement C1r-A subcomponent; Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain; Complement component 1 subcomponent r; Complement component 1 subcomponent r-A; complement component 1, r subcomponent; complement component 1, r subcomponent A; complement component 1, r-A subcomponent; mC1rA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 715
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00736
• Gene Symbols: C1R
• Immunogen: Recombinant Human C1r. Recombinant protein control fragment (Product #RP-105682).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov