Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ C1S (Active) Monoclonal Antibody (M241)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548987

Catalog No. FERMA548987


Only null left
Add to Cart

Description

Description

The epitope recognised by the antibody M241 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M241 blocks C4 activation and C4 binding to activated C1s. The antibody binds specifically to the active centre of C1s.

Activated C1s is a protein complex involved in the complement system, which is a part of the innate immune system. C1s is a serine protease that cleaves C4 and C2 in the classical pathway of complement activation, leading to the formation of C3 convertase. The activation of C1s is initiated by binding of C1q to antigen-antibody complexes or other ligands. The C1s protein is encoded by the C1S gene, which is located on chromosome 12. Dysregulation of the complement system and C1s activation has been implicated in various diseases, including autoimmune disorders, infections, and inflammatory conditions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

C1S (Active)
Monoclonal
100 μg/mL
PBS with 0.1% BSA and no preservative
P09871
C1S
Monoclonal antibody M241 reacts with an epitope on human C protein activated C1s.
100 μg
Primary
Human
Antibody
IgG2a
Flow Cytometry, Functional Assay, Inhibition Assays, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
M241
Unconjugated
C1S
Active C1S; C1S; C1s1
Mouse
Protein G
RUO
716
4°C
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.