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Invitrogen™ C1S Monoclonal Antibody (M81)
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Catalog No. FERMA548990
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100 μg
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Catalog No. Quantity
FERMA548990 100 μg
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Catalog No. FERMA548990 Supplier Invitrogen™ Supplier No. MA548990
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Mouse Monoclonal Antibody

The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M81 blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C1S
Applications Flow Cytometry, Functional Assay, Inhibition Assays, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone M81
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene C1S
Gene Accession No. P09871
Gene Alias AA959438; AI255193; AI327365; basic proline-rich peptide IB-1; C1 esterase; C1s; C1s1; C1sa; complement C1s; complement C1s subcomponent; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain; Complement C1s-A subcomponent; Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain; Complement component 1 subcomponent s; complement component 1 subcomponent s-A; complement component 1, s subcomponent; complement component 1, s subcomponent 1; complement component C1SA; r-gsp; serine protease
Gene Symbols C1S
Host Species Mouse
Immunogen Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 716
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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