Invitrogen™ C1S Monoclonal Antibody (M81)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA548990

Catalog No. FERMA548990

Description

The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. Monoclonal antibody M81 blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.

Specifications

• Antigen: C1S
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: P09871
• Gene Symbols: C1S
• Immunogen: Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Functional Assay, Inhibition Assays, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: M81
• Conjugate: Unconjugated
• Gene: C1S
• Gene Alias: AA959438; AI255193; AI327365; basic proline-rich peptide IB-1; C1 esterase; C1s; C1s1; C1sa; complement C1s; complement C1s subcomponent; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain; Complement C1s-A subcomponent; Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain; Complement component 1 subcomponent s; complement component 1 subcomponent s-A; complement component 1, s subcomponent; complement component 1, s subcomponent 1; complement component C1SA; r-gsp; serine protease
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 716
• Content And Storage: 4°C
• Form: Liquid