Invitrogen™ C21orf2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531331

Catalog No. PIPA531331

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.

Specifications

• Antigen: C21orf2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CFAP410
• Gene Alias: C21orf2; C21orf-HUMF09G8.5; cDNA A2-YF5; CFAP410; chromosome 21 open reading frame 2; Cilia- and flagella-associated protein 410; cu002; leucine rich repeat containing 76; leucine-rich repeat-containing protein 76; LRRC76; nuclear encoded mitochondrial protein C21orf2; protein C21orf2; YF5; YF5/A2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 755
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.72 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43822
• Gene Symbols: CFAP410
• Immunogen: Recombinant protein encompassing a sequence within the center region of human C21orf2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov